Melatonin, the best antidote to inflammatory diseases
Melatonin is a hormone that we naturally secrete and which plays countless roles in our bodies: including the regulation of sleep, stimulation of the immune system, a reduction in oxidative stress, etc.). When produced by chemical synthesis, this substance also has many possibilities in the pharmaceutical industry. The Intercellular Communication Laboratory at the University of Granada has been looking for medical applications for this compound for many years. One of its most promising projects aims to use this hormone to reduce the effects of inflammatory diseases.
Thus, sepsis, a disorder known in medicine as a systemic inflammatory response syndrome (SIRS), is caused by a serious infection which, in its most advanced form, results in the multiorgan failure that causes death. But, according to Andalucía Innova, melatonin may be the solution in the fight against the inflammation which causes this pathology.
The principal investigators responsible for this research, Darío Acuña Castroviejo and Germaine Escames, will soon begin the first clinical trials of melatonin in this context, at the Virgen de las Nieves Hospital in Granada. These scientists are also collaborating with researchers from the Faculty of Pharmacy to prepare new drugs, designed by chemical synthesis, that have the same properties as melatonin.